Associação entre Bisfenol A e Ftalatos e o desenvolvimento da puberdade precoce em meninas

Authors

  • Taciana Maria Soriano
  • Bianca Pereira Bachião
  • Isabela Bogado de Bem
  • Bárbara Cristina Dias Gonçalves
  • Alice Magalhães Souto Cunha Duarte

DOI:

https://doi.org/10.46919/archv4n3-019

Keywords:

puberdade precoce, disruptores endócrinos, Bisfenol A (BPA), Ftalatos

Abstract

A exposição a produtos químicos presentes no meio ambiente podem afetar as vias moleculares genéticas e epigenéticas, o que leva a alterações no crescimento e desenvolvimento de organismos. Entre essas substâncias químicas, os disruptores endócrinos são uma preocupação especial, pois seres humanos são largamente expostos a esses produtos químicos. Vários produtos químicos ambientais conhecidos, incluindo ftalatos e bisfenol A (BPA), são classificados como disruptores endócrinos. Eles podem similar, bloquear ou modular a síntese, a liberação, o transporte, o metabolismo e a ligação ou eliminação de hormônios, o que pode desencadear a puberdade precoce central em crianças do sexo feminino. Puberdade precoce é descrita como o início do desenvolvimento de características sexuais secundárias antes dos oito anos de idade em meninas. O objetivo deste estudo é revisar a literatura médica dos últimos anos que analisaram as associações entre a exposição ao BPA e aos ftalatos e a idade do início da puberdade em meninas.

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Published

2023-09-27

How to Cite

SORIANO, T. M.; BACHIÃO, B. P.; DE BEM, I. B.; GONÇALVES, B. C. D.; DUARTE, A. M. S. C. Associação entre Bisfenol A e Ftalatos e o desenvolvimento da puberdade precoce em meninas. Journal Archives of Health, [S. l.], v. 4, n. 3, p. 936–952, 2023. DOI: 10.46919/archv4n3-019. Disponível em: https://ojs.latinamericanpublicacoes.com.br/ojs/index.php/ah/article/view/1417. Acesso em: 19 apr. 2024.